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Added April 7, 2018 by Tekla User Assistance [email protected]

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Einige Komponentendialogfelder enthalten die Registerkarte Entwurf , andere die Registerkarte Design-Typ . Prüfen Sie anhand der Optionen auf diesen Registerkarten, ob die Komponente die Gleichlast (UDL, Uniform Distributed Load) tragen kann. Einige Registerkarten Entwurf enthalten nur die Entwurfsprüfung. Tekla Structures speichert die Entwurfszusammenfassung als .txt -Datei im Modellordner.

Sie können AutoDefaults predefined properties that AutoConnection uses when creating connections -Regelgruppen und Excel-Dateien in der Entwurfsprüfung verwenden:

Weitere Informationen finden Sie unter Verwenden von Stabkräften und UDLs in AutoConnection und AutoDefaults .

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Für diese Entwurfprüfung wird das englische Maßsystem verwendet.

So verwenden Sie die Entwurfsprüfung:

Siehe auch Excel-Tabellen im Verbindungsentwurf .

Tekla Structures überprüft die Komponente. Erscheint das Verbindungssymbol in grün, so hält die Verbindung der UDL stand. Andernfalls erscheint das Symbol in rot.

Das Dialogfeld Objektinformation zeigt die Zusammenfassung der Entwurfsprüfung und weitere Informationen an.

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Für diese Entwurfprüfung wird das englische Maßsystem verwendet.

So verwenden Sie die Entwurfsprüfung:

Tekla Structures überprüft die Verbindung jedes Mal, wenn sie im Modell verwendet wird oder geändert wird.

Das Dialogfeld Objektinformation zeigt die Zusammenfassung der Entwurfsprüfung an: das geprüfte Teil, der Name der Prüfung, die angewendete und zulässige Kraft sowie die benötigte Kapazität, die Ergebnisse und mögliche Lösungen.

Der Entwurf basiert auf dem britischen Standard BS5950.

Dieser Entwurf unterliegt den folgenden Einschränkungen:

Zugkraft ist erforderlich, wenn die Entwurfsprüfung aktiviert ist und es sich bei dem Rahmentypen der Verbindung um eine Träger-an-Stütze handelt. Wenn keine Zugkraft vorhanden ist, geben Sie 0 ein.

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Claude led the Hull Olympiques to a President Cup championship in 1996 97. In his only year coaching in the QMJHL, Hull finished first overall in the fourteen team league with 48 wins and 99 points in 70 games. The Olympiques went 12 2 in the playoffs and swept the Chicoutimi Sagueneens in the finals.

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Pathway for the movement of acetyl-CoA units from within the mitochondrion to the cytoplasm. Under high energy charge mitochondrial acetyl-CoA and citrate accumulate due to allosteric inhibition of the TCA cycle. Due to accumulating acetyl-CoA, pyruvate carboxylase is highly activated allowing for continued synthesis of oxaloacetate ensuring the eventual sysnthesis of citrate. SLC25A1 is the citrate transporter (also called the dicarboxylic acid transporter). Transport of pyruvate across the plasma membrane is catalyzed by the Alaïa Leather RoundToe Boots Cheap Cheap Online Outlet Low Price Fee Shipping For Sale Online Many Kinds Of Cheap With Credit Card xbqKCDFK
protein (also called the monocarboxylic acid transporter 1, MCT1) and transport across the outer mitochondrial membrane involves a voltage-dependent porin transporter. Transport across the inner mitochondrial membrane requires a heterotetrameric transport complex (mitochondrial pyruvate carrier) consisting of the MPC1 gene and MPC2 gene encoded proteins. Note that the cytoplasmic malic enzyme (encoded by the ME1 gene) catalyzed reaction generates NADPH which can be used for reductive biosynthetic reactions such as those of fatty acid and Sale Genuine Prada RoundToe Platform Pumps Best Seller GxJRi9
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Pathway for the movement of acetyl-CoA units from within the mitochondrion to the cytoplasm.

Acetyl-CoA enters the cytoplasm in the form of citrate via the tricarboxylate transport system (encoded by the SLC25A1 gene; see Figure). In the cytoplasm, citrate is converted to oxaloacetate and acetyl-CoA by the ATP driven ATP-citrate lyase reaction. This reaction is essentially the reverse of that catalyzed by the TCA enzyme citrate synthase except it requires the energy of ATP hydrolysis to drive it forward. The resultant oxaloacetate is converted to malate by cytoplasmic malate dehydrogenase (encoded by the MDH1 gene). ATP-citrate lyase is encoded by the ACYL gene which is located on chromosome 17q21.2 and is composed of 30 exons that generate four alternatively spliced mRNAs, each of which encoded a unique protein isoform.

The malate produced by this pathway can undergo oxidative decarboxylation by cytoplasmic malic enzyme (ME1). The co-enzyme for this reaction is NADP + generating NADPH. The advantage of this series of reactions for converting mitochondrial acetyl-CoA into cytoplasmic acetyl-CoA is that the NADPH produced by the malic enzyme reaction can be a major source of reducing co-factor for the fatty acid synthase activities.

Humans express three malic enzymes, one cytoplasmic that requires NADP + and two mitochondrial enzymes, one that requires NADP + and one that requires NAD + . The cytoplasmic enzyme is called malic enzyme 1 and is encoded by the ME1 gene that is located on chromosome 6q14.2 and is composed of 14 exons that encode a protein of 572 amino acids. The NAD + -dependent mitochondrial enzyme is called malic enzyme 2 and is encoded by the ME2 gene located on chromosome 18q21.2 and is composed of 16 exons that generate two isoforms from alternatively spliced mRNAs. The NADP + -dependent mitochondrial enzyme is called malic enzyme 3 and is encoded by the ME3 gene located on chromosome 11q14.2 and is composed of 22 exons that generate four alternatively spliced mRNAs that all encode the same 604 amino acid protein.

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